A LC–MS/MS method to obtain the specificity required for accurate measure-ment of GLP-1. Many properties of IA LC– MS/MS are the same as immunoassays, with the added benefit that...
A UHPLC/MS/MS method for the analysis of active and inactive forms …
Jan 1, 2022 · Hence, the present study is aimed at developing a robust and reliable methodology for the identification and quantification of active and inactive forms of the incretins GLP-1 and …
An ultrasensitive method for the quantitation of active and inactive ...
Jan 1, 2014 · We have developed a robust analytical method for the quantitation of endogenous active and inactive GLP-1 in human plasma. In addition, we employed this method to measure …
Tools and Techniques for GLP-1 Analysis | LCGC International
Jun 9, 2025 · This article outlines current and emerging trends in the analysis of GLP-1 receptor agonists, with a focus on liquid chromatography (LC), mass spectrometry (MS), and regulatory …
This application note presents an automated workflow using LC/MS to quantify the GLP-1 analog semaglutide in human plasma.
This work will demonstrate a robust microflow LC-MS/MS system to measure commercially available GLP-1 analogs with increased sensitivity compared to conventional semi- microflow …
Sensitive LC-MS method for the quantitative analysis of …
We demonstrated a comprehensive LCMS solution for highly sensitive quantitation of GLP-1 analogs in human plasma using the Vanquish UHPLC coupled to TSQ Altis Plus MS.
In this workflow, a sensitive LC-MRM method was developed for the quantification of GLP-1 analogue, liraglutide, in rat plasma. All method parameters were carefully optimized to ensure …
An ultrasensitive method for the quantitation of active and inactive ...
We performed fit-for-purpose validation of the assay by assessing the following assay performance characteristics: inter-assay precision, sensitivity, spike recovery, dilution linearity, …
A UHPLC/MS/MS method for the analysis of active and inactive …
Jan 1, 2022 · Based on these premises, the present study is aimed at developing a robust and reliable methodology for the identification and quantification of active and inactive forms of …
Sensitive methods are needed to effectively detect and quantify GLP-1 analogs in biological matrices. The presented method demonstrates a quantitative method for a commercially …
This application note describes a workflow for LC/MS analysis of liraglutide and its impurities, using reversed-phase chromatography combined with Q-TOF MS/MS detection. Liraglutide is …